Spurs carry a 2-0 lead from the first leg of the tie as they travel to take on Dinamo Zagreb at the Stadion Maksimir.
Tottenham have a strong record of progressing in Europa League ties after winning their first leg with a perfect 3 from 3 record in the competition.
Their record on the road in Europe is also particularly good with three wins and two losses in their last five games.
Jose Mourinho revealed that Harry Kane will be fit for the match, but that Heung-min Son won’t play a part after picking up an injury over the weekend.
The hosts have endured a chaotic week after their head coach was Zoran Mamic was forced to resign due to being found guilty of fraud. A managerless team could pose a potential banana skin to Spurs as they look to progress.